国产与进口法莫替丁片治疗非糜烂性胃食管反流病的经济学评价

目的比较国产与进口法莫替丁片治疗非糜烂性胃食管反流病（NERD）的经济性及疗效。方法将50例NERD患者分成观察组和对照组。对照组用进口法莫替丁片＋埃索美拉唑镁肠溶片＋西沙必利片,观察组用国产法莫替丁片＋埃索美拉唑镁肠溶片＋西沙必利片。结果观察组治愈率为68.00%,有效率为28.00%,无效率为4.00%,总有效率为96.00%;对照组治愈率为72.00%,有效率为20.00%,无效率为8.00%,总有效率为92.00%。两组间疗效比较,差异均无显著性（P〉0.05）。两组患者均未见明显不良反应。法莫替丁片国产价格低于进口。结论国产法莫替丁片联合埃索美拉唑镁肠溶片及西沙必利片治疗NERD疗效可靠,安全,经济实惠。

Economic Evaluation of Domestic and Imported Famotidine Tablets for Treating Non-Erosive Gastroesophageal Reflux Disease

Objective To compare the effect and economy between domestic and imported famotidine tablets for treating non-erosive gastroesophageal reflux disease（NERD）.Methods 50 cases of NERD were divided into the observation group and the control group.The control group was given with imported famotidine tablets ＋ esomeprazole magnesium enteric-coated tablets ＋ cisapride tablet,while the observation group with domestic famotidine tablets ＋ esomeprazole magnesium enteric-coated tablets ＋ cisapride tablet.Results In the observation group,the cure rate was 68.00%,the effective rate was 28.00%,the ineffective rate was 4.00% and the total effective rate was 96.00%.In the control group,the cure rate was 72.00%,effective rate was 20.00%,the ineffective rate was 8.00% and the total effective rate was 92.00%.The difference of the curative efficacy between the two groups was not significant（P 0.05）.No significant adverse reactions were found in the two groups.The price of domestic famotidine tablets was lower than that of imported ones.Conclusion Domestic famotidine tablets combined with esomeprazole magnesium enteric-coated tablets and cisapride tablet is safe,economic and practical with reliable effect for treating NERD.