化妆品皮肤损伤989例分析

目的 探讨化妆品皮肤损伤状况和病因及发生规律。方法 对989例化妆品皮肤损伤进行了临床观察，并用辨敏牌标准筛选斑贴试验试剂盒对患者做斑贴试验。结果 临床表现主要为接触性皮炎(70．58％)，其次是色素沉着(11．02％)、痤疮样损害(7．99％)、光感性皮炎(1．01％)、混合性皮损(9．40％)。可疑致病化妆品种类189种。989例患者中阳性者653例，阳性率66．03％。结论 斑贴试验对接触性皮炎、色素沉着类化妆品皮肤损伤有确定的指导、防治意义，化妆品皮肤损伤应进行斑贴试验。

Cosmetic dermatosis: clinical analysis of 989 cases

Objective To study the characteristics of cosmetic dermatosis and to determine the allergens for cosmetic dermatosis. Methods Unwanted effects of cosmetics in the 989 patients were observed and the patch test was performed in all patients with Bianmin standard screening patch test kit. Results Of them 698 (70.58 %) were contact dermatitis, 109 (11.02 %) were hyperpigmentation, and 79 (7.99 %) were acne like lesions. One hundred and eighty-nine kinds of cosmetics were suspected to be responsible for the dermatosis. 653 out of 989 patients tested were positive (66.03%). Conclusions Cosmetic dermatosis such as contact dermatitis and hyperpigmentation can be prevented and cured by guidance of patch test. The patch test should be performed in patients with cosmetic dermatosis.