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Effect of S1P5 on proliferation and migration of human esophageal cancer cells |
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| Authors: | Wei-Min Hu Li Li Bao-Qian Jing Yong-Sheng Zhao Chao-Li Wang Li Feng Yong-En Xie |
| Institution: | Wei-Min Hu, Department of Microbiology and Immunology, North Sichuan Medical College, Nanchong 637007, Sichuan Province, ChinaLi Li, Bao-Qian Jing, Chao-Li Wang, Li Feng, Yong-En Xie, Institute of Immunology and Molecular Biology, North Sichuan Medical College, Nanchong 637007, Sichuan Province, ChinaYong-Sheng Zhao, Department of Thoracic Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong 637007, Sichuan Province, China |
| Abstract: | AIM:To investigate the sphingosine 1phosphate (S1P) receptor expression profile in human esophageal cancer cells and the effects of S1P5 on proliferation and migration of human esophageal cancer cells. METHODS: S1P receptor expression profile in human esophageal squamous cell carcinoma cell line Eca109 was detected by semiquantitative reverse trans cription polymerase chain reaction. Eca109 cells were stably transfected with S1P5EGFP or controlEGFP constructs. The relation between the responses of cell prol... |
| Keywords: | Sphingosine 1-phosphate Esophageal cancer Sphingosine 1-phosphate 5 Proliferation Migration |
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