| 中药配方颗粒剂质量控制研究现状及展望 |
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| 引用本文： | 陈昭,毕晓黎,邱宏聪,孙冬梅.中药配方颗粒剂质量控制研究现状及展望[J].中国民族民间医药杂志,2013(20):11-13,15. |
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| 作者姓名： | 陈昭 毕晓黎 邱宏聪 孙冬梅 |
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| 作者单位： | [1]广东省中医药工程技术研究院,广东广州510095 [2]广西壮族自治区中医药研究院,广西南宁530022 |
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| 基金项目： | 广西中医药研究院重点实验室开放课题（省级,桂中重开201201）. |
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| 摘 要： | 对中药配方颗粒剂质量控制的技术手段进行全面的评述,分析各种技术的优缺点、应用范围等特点.在现有研究成果的基础上,探讨配方颗粒剂质量控制标准化、现代化以及考察内容全面化的可能性.由于配方颗粒剂仍为中药材提取液所得制剂,有大量结构和活性相似的化合物.因此,本文重点论述如何采用各类仪器分析技术及前处理手段,提高质量标准研究和指纹图谱建立过程的确定性、针对性和全面性.另外,对于配方颗粒剂与传统中药方剂在药效学和药动学上的差异,相关研究领域一直存在较大空白,如何填补这些空白,也是本综述的意图之一.
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| 关 键 词： | 中药配方颗粒 质量控制 分析技术 展望 |
Applications and perspectives of quality control on TCM granule |
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| Institution: | CHEN Zhao BI Xiao - li QIU Hong - cong SUN Dong - mei (1 Guangdong Province Engineering Technology Research Institute of TCM, guangzhou guangdong 510095 ; 2. Guangxi Institute of Chinese Medicine and Pharmaceutical Science, harming guangxi 530022) |
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| Abstract: | Technologies and methodologies of quality control for TCM granule were evaluated in this review, focusing on their ad- vantages, disadvantages and applications. Based On recent achievements, we summarized data and reports for the assessment of possi- bilities in standardization, further modernization and comprehensive evaluation. Therefore, this review dedicated to improve determina- cy, specificity and ability to comprehensive analysis, which can be done by wise selection and integration of current techniques. Addi- tionally, to answer the question of difference in pharmacokinetic parameters between TCM granule and other traditional formulas, con- siderable amount of efforts should be done to fill great blank existed. |
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| Keywords: | TCM granule quality control analytical technologies perspectives |
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