| 肠道疾病治疗中的口服结肠靶向给药系统 |
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| 引用本文： | 王兰,杨芳,齐香君. 肠道疾病治疗中的口服结肠靶向给药系统[J]. 中国新药杂志, 2003, 12(12): 995-998 |
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| 作者姓名： | 王兰 杨芳 齐香君 |
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| 作者单位： | 陕西科技大学,咸阳,712081 |
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| 摘 要： | 口服结肠靶向给药在治疗肠道疾病方面具有使用方便、结肠部位药物浓度较高的优点；其应用类型有3种：利用结肠特殊生理特性、靶向免疫调节细胞和生物黏附原理的结肠靶向给药系统。现对此3种口服结肠靶向给药系统的制备和应用进行综述。
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| 关 键 词： | 口服结肠靶向给药系统 肠道疾病 生物黏附 |
| 文章编号： | 1003-3734(2003)12-0995-04 |
Oral colon specific targeting drug-delivery system in management of gastroi-ntestinal diseases |
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| WANG Lan,YANG Fang,QI Xiang-jun. Oral colon specific targeting drug-delivery system in management of gastroi-ntestinal diseases[J]. Chinese Journal of New Drugs, 2003, 12(12): 995-998 |
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| Authors: | WANG Lan YANG Fang QI Xiang-jun |
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| Abstract: | The oral colon specific targeting drug-delivery system(OCSTDS) are easy to use and can increase the local drug level of colon in treatment of gastrointestinal diseases. There are 3 types: OCSTDS by use of the particular physiological characteristics of colon, OCSTDS by use of targeting immune-regulating cells, and OCSTDS by use of bioadhesive principle. The preparation and application of the 3 types of OCSTDS were reviewed in this paper. |
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| Keywords: | oral colon specific targeting drug-delivery system gastrointestinal disease bioadhesion |
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