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Experimental system for perfusion imaging and time-intensity processing based on ultrasound contrast agent
引用本文:宋延淳 万明习 吴方刚 樊华 宗瑜瑾. Experimental system for perfusion imaging and time-intensity processing based on ultrasound contrast agent[J]. 中国人民解放军军医大学学报, 2006, 21(1): 38-41
作者姓名:宋延淳 万明习 吴方刚 樊华 宗瑜瑾
作者单位:Key Laboratory of Biomedical Information Engineering of Ministry of Education ,and Department of Biomedical Engineering ,School of Life Science and Technology,Xi'an Jiaotong University ,Xi'an 710049 ,China
摘    要:Objective: To present a self-developed experimental system for basic studies of blood perfusion imaging and time-intensity evaluating based on ultrasound contrast agent. Methods : The experimental system performed the image reconstruction and time-intensity processing with radio frequency signals. The system was comprised of ultra-high speed hardware data acquisition interface and low computational cost algorithms. The self-made contrast agent ,blood mimic phantom and capillary phantom model were used to validate the experimental system. Results: The images acquired in blood phantoms with linear-array and curve-array transducers were given. The time-intensity curves corresponding to selected region of interestsequence were demonstrated. It was also shown the time-intensity based decay curves and a decay of ultrasound contrast agent under different ultrasound powers. Conclusion: Several suited from two in vitro phantom models show that the experimental system can be used to f blood perfusion and further clinical studies of microvasculature perfusion.

关 键 词:实验室 超声检查 药剂 超声强度
收稿时间:2005-10-10
修稿时间:2005-12-20

Experimental system for perfusion imaging and time-intensity processing based on ultrasound contrast agent
SONG Yan-chun,WAN Ming-xi,WU Fang-gang,FAN Hua,ZONG Yu-jin. Experimental system for perfusion imaging and time-intensity processing based on ultrasound contrast agent[J]. Journal of Medical Colleges of PLA(China), 2006, 21(1): 38-41
Authors:SONG Yan-chun  WAN Ming-xi  WU Fang-gang  FAN Hua  ZONG Yu-jin
Abstract:Objective:To present a self-developed experimental system for basic studies of blood perfusion imaging and time-intensity evaluating based on ultrasound contrast agent. Methods: The experimental system performed the image reconstruction and time-intensity processing with radio frequency signals. The system was comprised of ultra-high speed hardware data acquisition interface and low computational cost algorithms. The self-made contrast agent,blood mimic phantom and capillary phantom model were used to validate the experimental system. Results: The images acquired in blood phantoms with linear-array and curve-array transducers were given. The time-intensity curves corresponding to selected region of interested from image sequence were demonstrated. It was also shown the time-intensity based decay curves and a comparison of decay of ultrasound contrast agent under different ultrasound powers. Conclusion: Several experiments resulted from two in vitro phantom models show that the experimental system can be used to basic studies of blood perfusion and further clinical studies of microvasculature perfusion.
Keywords:perfusion imaging  time-intensity processing  ultrasound contrast agent
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