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Hedgehog signaling in mature osteoblasts regulates bone formation and resorption by controlling PTHrP and RANKL expression
Affiliation:1. Department of Cranio-Maxillofacial and Oral Surgery, Medical University of Innsbruck, Maximilianstrasse 10, 6020 Innsbruck, Austria;2. Institute for Biophysics, Johannes Kepler University of Linz, Altenbergerstrasse 69, 4040 Linz, Austria;3. Department of Materials Chemistry, Angstrom Laboratory, Uppsala University, Lägerhyddsvägen 1, Box 538, S-75121 Uppsala, Sweden;4. University Hospital of Cranio-Maxillofacial and Oral Surgery, Medical School, University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria;5. Institute for Biomedical Aging Research, Austrian Academy of Sciences, Rennweg 10, 6020 Innsbruck, Austria;6. Department of Histology and Embryology, Müllerstrasse 59, 6020 Innsbruck, Austria;7. ρ-BeSt coating GmbH, Exlgasse 20a, 6020 Innsbruck, Austria;1. Department of Developmental Neurobiology, St. Jude Children''s Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA;2. Department of Pathology and Laboratory Medicine, The Joseph Stokes Jr. Research Institute, The Children''s Hospital of Philadelphia, 517 Abramson Research Center, 3615 Civic Center Boulevard, Philadelphia, PA 19104, USA;1. Department of Orthodontics and Dentofacial Orthopedics, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata, Okayama-City, Okayama, 700-8525, Japan;2. Department of Physiology, Kawasaki Medical School, Matushima 57, Kurashiki-city, Okayama, 701-0192, Japan;3. Department of Medical Engineering, Kawasaki Medical School, Matushima 57, Kurashiki-city, Okayama, 701-0192, Japan;4. Division of Orthodontics and Dentofacial Orthopedics, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai-City, Miyagi, 980-8574, Japan;1. Applied Physiology, Georgia Institute of Technology College of Sciences, Atlanta GA 30332, USA;2. Veterans Affairs Medical Center, Atlanta GA 30033, USA;3. Department of Pediatrics, Emory University School of Medicine, Atlanta GA 30322, USA;4. Laboratory of Immunology and Genetics, Istituti Ortopedici Rizzoli, Bologna, Italy;5. Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
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