| 马蓝种质资源研究进展 |
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| 引用本文： | 周正,郭志英,谭何新,刘佳颖,刁勇,张磊.马蓝种质资源研究进展[J].药学实践杂志,2017,35(1):1-5,16. |
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| 作者姓名： | 周正 郭志英 谭何新 刘佳颖 刁勇 张磊 |
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| 作者单位： | 第二军医大学药学院药用植物学教研室, 上海 200433,第二军医大学药学院药用植物学教研室, 上海 200433;华侨大学生物医学学院, 福建 泉州 362021,第二军医大学药学院药用植物学教研室, 上海 200433,第二军医大学药学院药用植物学教研室, 上海 200433,华侨大学生物医学学院, 福建 泉州 362021,第二军医大学药学院药用植物学教研室, 上海 200433 |
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| 基金项目： | 国家自然科学基金-促进海峡两岸科技合作联合基金资助项目（U1405215）;第二军医大学大学生创新实践课题-马蓝转录组测序数据分析及关键基因筛选（F2015094） |
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| 摘 要： | 马蓝,广泛分布于我国西南、华南及华东地区,是重要的爵床科药用植物。由其茎、叶加工而成的青黛,以福建产品质最佳,被誉为建青黛,是福建道地药材。马蓝的根入药称南板蓝根,与青黛一起同为《中华人民共和国药典》药材品种。青黛及其原植物马蓝的指标性成分靛玉红（indirubin）是具有抗白血病功效的中成药“黄黛片”及“当归龙荟丸”的主要活性成分。笔者主要综述了马蓝种质资源的分布、生物学特征、栽培技术和分子生物学等国内外研究进展,并提出了马蓝种质资源面临的主要问题,为马蓝及青黛的相关研究与应用提供参考依据。
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| 关 键 词： | 马蓝 种质资源 生物学特性 栽培技术 遗传多样性 |
| 收稿时间： | 2016/1/4 0:00:00 |
| 修稿时间： | 2016/6/20 0:00:00 |
Progress on germplasm resources of Baphicacanthus cusia(Nees) Bremek |
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| ZHOU Zheng,GUO Zhiying,TAN Hexin,Liu Jiaying,DIAO Yong and ZHANG Lei.Progress on germplasm resources of Baphicacanthus cusia(Nees) Bremek[J].The Journal of Pharmaceutical Practice,2017,35(1):1-5,16. |
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| Authors: | ZHOU Zheng GUO Zhiying TAN Hexin Liu Jiaying DIAO Yong and ZHANG Lei |
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| Affiliation: | Department of Pharmaceutical Botany, School of Pharmacy, Second Military Medical University, Shanghai 200433, China,Department of Pharmaceutical Botany, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;School of Biomedical Science, Institutes of Molecular Medicine, HuaqiaoUniversity, Quanzhou 362000, China,Department of Pharmaceutical Botany, School of Pharmacy, Second Military Medical University, Shanghai 200433, China,Department of Pharmaceutical Botany, School of Pharmacy, Second Military Medical University, Shanghai 200433, China,School of Biomedical Science, Institutes of Molecular Medicine, HuaqiaoUniversity, Quanzhou 362000, China and Department of Pharmaceutical Botany, School of Pharmacy, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | Baphicacanthus cusia, widely distributed in the Southwest, Southern and Eastern regions of China, is an important medicinal plant of Acanthaceae family. Indigo made from stem and leaf of Baphicacanthus cusia in Fujian has the best quality in China, and is known as "Jian Indigo naturalis", which is the genuine medicinal of Fujian Province. The rhizoma of Baphicacanthus cusia could be used as medicine, called "Nanbanlangen", which together with indigo were included in the "Chinese Pharmacopoeia". Indigo and its original plant both contain indirubin, which has anti-cancer activity. Indirubin is an active ingredient of Huangdai Pian and Danggui Longhui Wan, two kinds of traditional Chinese medicine, which have been successfully used in the treatment of malignancies such as chronic myelogenous leukemia. The international advances in the biological characteristics, genetic diversity, cultivation technology and molecular biology of Baphicacanthus cusia germplasm resources were summarized. The main problems in Baphicacanthus cusia germplasm resources research are indicated, which could provide references for the further study and application of Baphicacanthus cusia germplasm resources. |
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| Keywords: | Baphicacanthus cusia germplasm resources biology characteristics cultivation technology genetic diversity |
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