成人牙周炎患者全唾液无机物水平分析

目的：分析全唾液部分无机物水平与成人牙周炎之间的相关关系。方法：收集活动期成人牙周炎患者（AP组）25例，年龄、性别配对正常对照（N组）25例。采集非刺激性全唾液，自动分析仪测定唾液中总钙(TCa)、磷（P）、镁（Mg^2 )、钠（Na^ )、钾（K^ )、氯（Cl^-)浓度。AP组进行临床牙周检查与记录，基础治疗后4周重复测定以上各指标。结果：AP组基础治疗后牙周袋探诊深度、牙龈指数、探诊出血、牙石指数显著下降；AP组唾液TCa、Na^ 浓度显著高于N组；治疗后TCa浓度无显著性变化，Na^ 浓度显著下降，与正常对照无显著性差异；Na^ 初诊浓度与探诊深度、牙龈指数值呈显著正相关。结论：牙周炎患者唾液TCa浓度升高为患者唾液中的特征性因素，有利于牙周炎的发生、发展；Na^ 浓度可反映牙周袋深度及牙龈炎症程度，与牙周炎病程、病情密切相关。

Concentration of SomeMinerals in Whole Saliva from Patients with Adult Periodontitis

Objective: Our aim was to analyze the relationship between the concentration of some minerals in saliva and periodontitis.Methods:Twenty five patients with adult periodontitis (AP group), 25 age and sex matched healthy people(N group) were selected. Unstimulated whole saliva samples were collected and qualified for the concentration of TCa,P,Mg 2 , Na ,K , and Cl -. Clinical parameters on periodontitis were also assessed for the patients. All the aforementioned indices were measured repeatedly at the end of the fourth week after initial therapy. Results:The clinical condition of the patients improved significantly after treatment. The level of saliva Ca elevated before and after treatment in AP group than that in N group. Before treatment, the concentration of Na also increased significantly, but it decreased to normal level after initial therapy. The findings also indicated the positive relationship between the concentration of salivary Na and pocket probing depth as well as gingival index before treatment.Conclusion:The elevated level of saliva Ca is a sign of periodontitis and may help the occurrence and progress of periodontitis. The level of saliva Na may indicate the pocket depth and degree of gingivitis.The saliva Na is closely associated with the clinical condition of periodontitis.