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我院339例药物不良反应分析
引用本文:魏娟娟,白玉国,魏国义.我院339例药物不良反应分析[J].中国医药,2010,5(6):534-536.
作者姓名:魏娟娟  白玉国  魏国义
作者单位:首都医科大学附属北京安贞医院药剂科,100029
摘    要:目的 分析我院药物不良反应(ADR)的发生特点及其引发的相关因素,促进临床合理用药,提高ADR监测工作质量.方法 对我院2008年1~12月收集的339例药物不良反应报告进行统计分析.结果 339例临床ADR病例报告中,引起不良反应最多的药物为抗感染药(220例,占57.0%),其次为中药制剂以及循环系统用药;最常见的临床表现为皮肤及其附件损害(150例,占44.2%);给药途径中以静脉给药发生频率最高(314例,占92.6%).结论 药物不良反应的发生与多种因素有关,合理用药是降低ADR发生的关键.

关 键 词:药物不良反应  合理用药  分析

Analysis of 339 cases of adverse drug reaction
WEI Juan-juan,BAI Yu-guo,WEI Guo-yi.Analysis of 339 cases of adverse drug reaction[J].China Medicine,2010,5(6):534-536.
Authors:WEI Juan-juan  BAI Yu-guo  WEI Guo-yi
Institution:.( Deptartment of Pharmacy, Beijing Anzhen Hospital of the Capital of University Medical Sciences, Beijing 100029, China)
Abstract:Objective To study the features of adverse drug reaction(ADR)and the relevant factors in order to promote clinical rational drug use and improve the quality of ADR monitoring.Methods A total of 339 cases of ADR reports collected in 2008 were classified and analyzed statistically.Results Of the total 339 ADR cases,the higheat incidence of ADRs were antimiembial drugs(220 cases,44.2%),followed by traditional Chinese medicine and circulatory system drugs.The main types of ADR were skin and appendages disorders(150 cases,44.2%).Intravenous infusion(314 cases,92.6%)was the main route of administration.Conclusions The occurrence of ADR is associated with a variety offactors.Clinical rational drug use is the key point of reducing the incidence of ADR.
Keywords:Adverse drug reaction  Rational drug use  Analysis
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