早期梅毒血清IL-37和IL-38的检测 |
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引用本文: | 张胜佳,李富容,刘丹璇,温晶,李珍,肖海璐,李中伟,郑荣涛,侯建玲. 早期梅毒血清IL-37和IL-38的检测[J]. 中国麻风皮肤病杂志, 2016, 0(2): 74-76 |
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作者姓名: | 张胜佳 李富容 刘丹璇 温晶 李珍 肖海璐 李中伟 郑荣涛 侯建玲 |
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作者单位: | 1. 济南大学山东省医学科学院医学与生命科学学院,济南, 250062;山东省皮肤病医院 山东省皮肤病性病防治研究所,济南, 250022;2. 山东省皮肤病医院 山东省皮肤病性病防治研究所,济南, 250022 |
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基金项目: | 山东省科技发展计划项目(2014GSF118104) |
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摘 要: | 目的:检测早期梅毒患者血清IL-37和IL-38的水平。方法:采用酶联免疫吸附法(ELISA)检测140例早期梅毒患者和180例正常对照血清IL-37、IL-38的表达水平。结果:早期梅毒患者血清中IL-37和IL-38的中位数分别为14.15 pg/m L和12.21 pg/m L,正常对照组分别为31.76 pg/m L和17.09 pg/m L,差异均有统计学意义(均P0.005)。结论:早期梅毒患者外周血清中IL-37和IL-38降低,可能与梅毒患者细胞免疫相关。
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关 键 词: | 早期梅毒 IL-37 IL-38 |
Detection of serum level of IL-37 and IL-38 in the patients with early syphilis |
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Abstract: | Objective:To detect the serum level of IL-37 and IL-38 in the patients with early syphilis. Methods:The level of IL-37 and IL-38 was detected with ELISA in 140 patients with early syphilis and 180 healthy controls. Results:The medians of IL-37 and IL-38 in patients of early syphilis were 14. 15 pg/mL and 12.21 pg/mL, which was lower than those of in healthy controls 31.76 pg/mL and 17.09 pg/mL (均P<0.05) . Conclusion:The level of IL-37 and IL-38 is lower in the patients with early syphilis, indicating that IL-37 and IL-38 may be involved in the cellular immunity. |
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Keywords: | early syphilis interleukin-37 interleukin-38 |
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