Nutritional therapy in inflammatory bowel disease |
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| Authors: | Piquet Marie-Astrid Gloro Romain Justum Anne-Marie Reimund Jean-Marie |
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| Affiliation: | 1. Department of Physiology, College of Medicine, Yeungnam University, South Korea;2. Department of Internal Medicine, Pusan National University Hospital, Pusan, South Korea;3. Department of internal Medicine, College of Medicine, Yeungnam University, Daegu, South Korea;4. Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, South Korea;1. Pediatric Emergency Department, Rambam Health Care Campus, Haifa Israel;2. Department of Pediatrics B, Rambam Health Care Campus, Haifa Israel;3. Pediatric Cardiology and Adults with Congenital Heart Disease, Rambam Health Care Campus, Haifa, Israel;4. Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel;1. Center for Clinical Epidemiology, Odense University Hospital, DK-5000 Odense C, Denmark;2. Research Unit of Clinical Epidemiology, Institute of Clinical Research, University of Southern Denmark, DK-5000 Odense C, Denmark;3. Department of Social Medicine, Aalborg University Hospital, DK-9000 Aalborg, Denmark;4. Department of Health Science and Technology, Faculty of Medicine, Aalborg University, DK-9000 Aalborg, Denmark;5. Department of Medical Gastroenterology S, Odense University Hospital, DK-5000 Odense C, Denmark;6. Research Unit of Medical Gastroenterology, Institute of Clinical Research, University of Southern Denmark, DK-5000 Odense C, Denmark;7. Department of Medical Gastroenterology, Aalborg University Hospital, DK-9000 Aalborg, Denmark;8. Department of Surgical Gastroenterology A, Odense University Hospital, DK-5000 Odense C, Denmark;9. Research Unit of Surgery, Institute of Clinical Research, University of Southern Denmark, DK-5000 Odense C, Denmark |
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| Abstract: | Protein-energy malnutrition and specific nutrient deficiencies are common in inflammatory bowel diseases (IBD), more particularly in Crohn's disease. In adults, the use of artificial nutrition is indicated in the event of malnutrition, short bowel syndrome, or IBD refractory to all other treatments. In children, enteral nutrition has a place as first-line treatment to avoid side effects of corticosteroids on growth. The use, as a therapeutic tool, of specific nutrients (n-3 fatty acids, glutamine, antioxydant vitamins and minerals, TGF-beta, probiotics...) seems interesting at the pathophysiological level. Nevertheless, these nutrients are still under evaluation and there are not enough available studies to recommend them in clinical routine. A very promising solution is the use of probiotics for the treatment of refractory pouchitis. |
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