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Central Nervous System Involvement in Congenital Visceral Fibromatosis
Authors:Edward D. Adickes   Paul Goodrich  Joseph Auchmoedy  Gayle Bickers  Bruce Bowden  Jack Koh  Robert M. Nelson  Robert M. Shuman  Richard B. Wilson
Affiliation: a Departments of Pathology and Laboratory Medicine, Pediatrics, Dermatology, Radiology, and Neurology, University of Nebraska Medical Center, Omaha, Nebraska
Abstract:Congenital visceral myofibromatosis is an uncommon disorder characterized by multiple tumors of myofibroblastic origin in the neonatal period. The natural history of the disorder has been well delineated. The myofibro blast is the cell of origin of the tumor. This is a report of a patient in whom multiple mesenchymal tumors occurred in the CNS as well as in other organs. Light and electron microiscopic findings of the CNS lesions are similar to those of the somites and viscera.
Keywords:central nervous system  congenital visceral fibromatosis
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