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难溶性药物渗透泵型控释制剂的研究进展
引用本文:甘勇,潘卫三,张汝华.难溶性药物渗透泵型控释制剂的研究进展[J].世界科学技术,2002,4(2):53-57.
作者姓名:甘勇  潘卫三  张汝华
作者单位:沈阳药科大学药学院 沈阳110016 (甘勇,潘卫三),沈阳药科大学药学院 沈阳110016(张汝华)
摘    要:本文从膜厚度,膜的机械穿透系数,包衣膜内外的渗透压差和药物溶解度四个方面,将难溶性药物制备渗透泵型控释制剂的研究进行了归纳总结,本文归总之研究,也为中药制剂研究提供了参考。

关 键 词:难溶性药物  渗透泵型控释制剂  中药制剂  包衣膜  机械穿透系数
修稿时间:2001年8月31日

Progress in Study on Delivery System of Osmotically Release-controlled and Poorly Water- soluble Drugs
Gan Yong,Pan Weisan and Zhang Ruhua.Progress in Study on Delivery System of Osmotically Release-controlled and Poorly Water- soluble Drugs[J].World Science and Technology(Modernization of Traditional Chinese Medicine),2002,4(2):53-57.
Authors:Gan Yong  Pan Weisan and Zhang Ruhua
Abstract:This article reviews the study on the delivery system of osmotically Release-controlled and poorly water-soluble drugs from the following four aspects: the thickness and the mechanical permeability of the membrane, the differences of the osmotic pressure and the solubility of Chinese drugs. This study may offer helpful reference for the study of the preparations of Chinese materia medica.
Keywords:poorly water-soluble drug  osmotic pump  release-controlled preperation  
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