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康复训练对A型肉毒毒素治疗痉挛型脑瘫长期疗效的影响
引用本文:刘建军,纪树荣,吴卫红,张雁,曾凡勇,李南玲. 康复训练对A型肉毒毒素治疗痉挛型脑瘫长期疗效的影响[J]. 中国康复理论与实践, 2011, 17(7): 654-656
作者姓名:刘建军  纪树荣  吴卫红  张雁  曾凡勇  李南玲
作者单位:1. 首都医科大学康复医学院,北京市,100068
2. 中国康复研究中心北京博爱医院儿童康复科,北京市,100068
摘    要:目的探讨康复训练对A型肉毒毒素(BTX-A)阻滞术缓解脑瘫患儿痉挛长期疗效的影响。方法 230例痉挛型脑瘫患儿接受BTX-A阻滞术治疗,根据患儿体重和修改的Ashworth量表(MAS)评分确定BTX-A剂量。A组每天进行康复训练2 h以上,B组进行康复训练2 h以下或无训练。1年后评定其粗大运动功能(GMFM)。结果 A、B两组患儿的年龄、体重、术前的MAS、GM-FM均无显著性差异(P>0.05),两组患儿肉毒毒素作用时间无显著性差异(P>0.05)。术后1年两组GMFM均较术前提高(P<0.05)。A组GMFM分数提高明显多于B组(P<0.01)。结论 BTX-A阻滞术后有肯定的长期疗效。阻滞术后开展康复训练有助于患儿粗大运动功能的提高。

关 键 词:脑性瘫痪  痉挛  A型肉毒毒素  长期疗效  神经阻滞  康复

Effect of Rehabilitation on Long-term Efficacy of Botulinum Toxin Type A on Spastic Cerebral Palsy
LIU Jian-jun,JI Shu-rong,WU Wei-hong,et al.. Effect of Rehabilitation on Long-term Efficacy of Botulinum Toxin Type A on Spastic Cerebral Palsy[J]. Chinese Journal of Rehabilitation Theory and Practice, 2011, 17(7): 654-656
Authors:LIU Jian-jun  JI Shu-rong  WU Wei-hong  et al.
Affiliation:LIU Jian-jun,JI Shu-rong,WU Wei-hong,et al.Capital Medical University School of Rehabilitation Medicine,Beijing Charity Hospital,China Rehabilitation Research Centre,Beijing 100068,China
Abstract:Objective To investigate the long-term efficacy of Botulinum toxin type A(BTX-A) on spasticity in cerebral palsy,and the effect of rehabilitation on it.Methods 230 children with spastic cerebral palsy were treated with BTX-A block.The dose of BTX-A was identified with the weight of the children and the Modified Ashworth Scale(MAS).They were divided into group A who exercised more than 2 h/d,and group B who exercised less than 2 h/d or not.They were assessed with Gross Motor Function Measure(GMFM) 1 year aft...
Keywords:cerebral palsy  spasticity  Botulinum toxin type A  long-term efficacy  nerve block  rehabilitation  
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