复发性多软骨炎致气道严重狭窄一例并文献复习

目的 总结复发性多软骨炎(RP)的临床表现以及气道受累的特点和治疗策略,提高对该病的认识.方法 报道1例RP合并严重气管狭窄的临床特点、诊治经过,并对该病进行文献复习.结果 患者为33岁女性,以咳嗽、声嘶、气短起病,3个月后确诊RP,此时已经出现严重的气管狭窄.糖皮质激素和免疫抑制剂治疗有效.结论 RP出现呼吸道受累并不少见,部分患者为首发症状.临床上应高度重视RP气道受累的早期诊治.否则预后不良.

Relapsing polychondritis with severe airway stenosis: report of a case and review of literature

Objective To summarize the clinic manifestations and treatment of relapsing polychondritis (RP) with airway stenosis. Method A case was reported and the literature was reviewed. Results A 32-year-old woman was diagnosed with RP based on the presences of cough, hoarseness and shortness of breath for 3months and severe tracheal stenosis was identified. Her clinical symptoms improved after being treated with glucocorticoid and immunosuppressive drugs. Conclusion Respiratory tract involvement in RP is not uncommon and it can be the initial symptom in some patients. Attention should be paid to RP when there is respiratory tract involvement in order to prompt early diagnosis and treatment. Delayed treatment can result in poor prognosis.