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IL-32在PR3-ANCA相关性血管炎中的表达水平的变化
引用本文:蔡安季,戴勇,郝建华,周天祥,沈化清,胡锋兰,苏卓娃. IL-32在PR3-ANCA相关性血管炎中的表达水平的变化[J]. 放射免疫学杂志, 2011, 24(3): 314-316
作者姓名:蔡安季  戴勇  郝建华  周天祥  沈化清  胡锋兰  苏卓娃
作者单位:1. 广东医学院附属南山医院,518052
2. 深圳市人民医院临床医学研究中心,518020
摘    要:目的:分析蛋白酶3-抗中性粒细胞抗体(proteimase 3-antineutrocyte antibody,PR3-ANCA)相关性血管炎患者外周血IL-32的表达,初步探讨IL-32在PR3-ANCA相关性血管炎的发病中的作用.方法:运用酶联免疫吸附试验(ELISA)检测PR3-ANCA相关性血管炎患者血清和外周...

关 键 词:白细胞介素-32  蛋白酶3-抗中性粒细胞抗体  血管炎

The Expression of Interleukin-32 in PR3-ANCA Associated Vasculitis
Cai An-ji,Dai Yong,Hao Jian-hua,et al.. The Expression of Interleukin-32 in PR3-ANCA Associated Vasculitis[J]. Journal of Radioimmanology, 2011, 24(3): 314-316
Authors:Cai An-ji  Dai Yong  Hao Jian-hua  et al.
Affiliation:Cai An-ji1,Dai Yong2,Hao Jian-hua1,et al.1Department of Clinical Laboratory,the Affiliated Nanshan Hospital of Guangdong Medical College,Shenzhen(518052),China 2Research Center of Clinical Medicine,Second Clinical Medical College,Jinan University,Shenzhen People's Hospital,Shenzhen(518020),China
Abstract:Objective To analyze the expressions of IL-32 and preliminary explore the role of IL-32 in the pathogenesis of PR3-ANCA associated Vasculitis.Methods The level of IL-32 in serum and supernatants of cultured PBMCs were detected by Enzyme-linked immunosorbent assay(ELISA).Results Compared with controls,the levels of IL-32 in serum and supernatants of cultured PBMCs were obviously higher.Conclusion The development of PR3-ANCA associated Vasculitis might be related closely with the expression of IL-32.
Keywords:IL-32  proteinase 3-antineutrocyte antibody(PR3-ANCA)  vasculitis  
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