JC Virus T-Antigen DNA in Gastrointestinal Mucosa of Immunosuppressed Patients: A Prospective,Controlled Study |
| |
| Authors: | Doron Boltin Alex Vilkin Zohar Levi Ori Elkayam Yaron Niv |
| |
| Affiliation: | (1) Department of Internal Medicine 6, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel;(2) Department of Gastroenterology, Rabin Medical Center, 39 Jabotinski Street, 49100 Petach Tikva, Israel;(3) Tel Aviv University, Tel Aviv, Israel; |
| |
| Abstract: | Background JC virus (JCV), a polyoma virus, is the etiological agent of progressive multifocal leukoencephalopathy in immunosuppressed patients. JCV T-Ag has proven oncogenic potential and is expressed in colonic polyps and carcinomas. We proposed that the prevalence of JCV T-Ag DNA is higher in the normal gastrointestinal (GI) mucosa of immunosuppressed patients compared with their immunocompetent counterparts. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
