不同海拔梯度严重创伤后诱发急性肺损伤的对比观察

目的：探讨不同海拔梯度创伤性ＡＬＩ／ＡＲＤＳ发病机制、几率、特征和早期防治。方法：按ＡＬＩ／ＡＲＤＳ记分标准将发生在海拔１５００（兰州）以胸伤为主与（或）多发伤病例，ＡＩＳ－ＩＳＳ院内记分在２０分以上的２６例列为Ａ组，将２２６０ｍ（西宁）伤情配比近似Ａ组的２２例列为Ｂ组，观察两组自受伤－－院内救护至发生ＡＬＩ／ＡＲＤＳ的时间、发病特点、几率、临床病征、血气变化。结果：在伤情相近，原发伤处理相近的条

Comparative observations of the post-traumatic acute lung injuries between gradient of 1500m and 2260m above sea level

Aim:To investigate risk factors of traumatic acute lung injury(ALI)/ARDS and it's pathophysiological mechanisms,and characteristic features at the different altitudes above sea level.Clinical material and methods:A standard couple test by AIS ISS scale were used both in high gradient of 1500m (group A,N=26) and 2260m(group B,N=22).The same parameters were recorded and measured at the same time intervals.Results:The results of this study showed that the clinical symptoms and signs,pathophysio characteristics and blood gas analysis were different significantly between group A and group B.Onset of the ALI/ARDS in group B was much earlier than group A and its clinical condition was much worse.Conclusions:ALI/ARDS happens above 2260m sea level may be a border line with it's mechanisms and pathophysio characteristics.Both hypoxia and trauma may play important role in formation of altitude ALI/ARDS.