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High-frequency oscillatory ventilation in ALI/ARDS
Authors:Ali Sammy  Ferguson Niall D
Affiliation:aInternal Medicine Program, Department of Medicine, University of Toronto, Toronto, Ontario, Canada;bInterdepartmental Division of Critical Care, University of Toronto, Toronto, Ontario, Canada;cDivision of Respirology, Department of Medicine, University Health Network and Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Abstract:In the last 2 decades, our goals for mechanical ventilatory support in patients with acute respiratory distress syndrome (ARDS) or acute lung injury (ALI) have changed dramatically. Several randomized controlled trials have built on a substantial body of preclinical work to demonstrate that the way in which we employ mechanical ventilation has an impact on important patient outcomes. Avoiding ventilator-induced lung injury (VILI) is now a major focus when clinicians are considering which ventilatory strategy to employ in patients with ALI/ARDS. Physicians are searching for methods that may further limit VILI, while still achieving adequate gas exchange.
Keywords:Acute respiratory distress syndrome   Acute lung injury   High-frequency oscillatory ventilation   Mechanical ventilatory support
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