模拟失重状态人脑波频率涨落分析

目的探讨短期模拟失重对人脑 7～ 1 2Hz频段脑波频率涨落特征的影响 ,为航天员脑功能选拔及训练监测提供功能性评价方法。方法 - 6°头低位卧床 (HDBR)模拟失重状态 ,记录 1 2名 1 8～ 2 2岁男性正常成人卧床前、卧床期间 (第 3、4、6天 )及恢复期 (卧床结束后第 3天 )清醒闭眼安静状态的EEG ,利用脑波频率涨落分析技术分析 7、8、9、1 0、1 1、1 2Hz 6个频率成分的优势涨落特征。结果卧床前 ,枕顶区优势涨落顺序为 1 0、9、1 1Hz;额颞区 1 0、9Hz竞争主优势成分 ,7Hz位居第 3。卧床后 ,各频率成分之间的主次地位和相互关系发生显著的可逆性变化 ,且所涉及的频率成分及脑区逐渐扩展 ,7、8Hz优势显著上升 ,1 0、1 1Hz优势显著下降 ,枕顶及后颞区 9、1 0Hz竞争主优势成分 ,7Hz位居第 3 ;额区及前颞区主次优势频率为 9、7Hz(F4为 7、9Hz) ,1 0Hz位居第 3。结论模拟失重导致脑波 7～ 1 2Hz频段频率涨落竞争结构显著改变 ,脑调节机能变差 ,易导致发作性头痛等临床症状 ,对脑功能造成潜在影响

Effects of Simulated Weightlessness on EEG Frequency Fluctuation Characteristics

Objective. To develop a method of EEG monitoring under special environment, which is of value for astronauts selection and training. Method. Weightlessness was simulated by means of -6 degrees head down bed rest (HDBR). Rest EEG was recorded in 12 male subjects (aged 18-22) with eyes-closed and then analyzed by means of EEG frequency-fluctuation analysis system. Result. Before HDBR, the dominant order at parietal and occiput was 10, 9, 11 Hz; At frontal and temporal regions 9 Hz competed with 10 Hz for the main dominant component, while the third was 7 Hz. During HDBR, reversible changes of position and interrelation between 7, 8, 9, 10, 11 and 12 Hz appeared, and the frequency components and their regions involved spread gradually. The probability of 7 Hz and 8 Hz dominance increased, while 10 Hz and 11 Hz dominance decreased. At parietal, occiput and post-temporal regions, 9 Hz competed with 10 Hz for the main dominant component, the third was 7 Hz. At frontal and pre-temporal regions, 9 Hz occupied the main dominant position, while the second was 7 Hz (at right-frontal regions, it even occupied the main dominant position), the third was 10 Hz. Conclusion. Simulated weightlessness cause change of EEG dominant-frequency fluctuation competitive structure significantly. Brain adaptation function decrease, and headache can be easily induced. There exists a potential influence on brain function.