罗哌卡因配伍曲马多用于术后硬膜外镇痛疗效分析

目的:观察罗哌卡因配伍曲马多用于术后硬膜外镇痛(postoperative extradural analgesia,PCEA)的效果。方法:50例行硬膜外麻醉手术者,术毕硬膜外导管接镇痛泵。镇痛泵药物配制:0.894%甲磺酸罗哌卡因20ml、曲马多0.8g、氟哌利多3~5mg,加生理盐水配至100ml。分别于术后9、12、24、36h观察疼痛评分、生命体征及并发症。结果:49例无痛,1例满意。30例发生嗜睡现象。50例中无恶心、呕吐、皮肤瘙痒、呼吸抑制发生,生命体征均平稳。结论:罗哌卡因配伍曲马多用于术后硬膜外镇痛有效、安全,副作用少。

The curative effect analysis of ropavacaine combined with tramadol for postoperative extradural analgesia

Objective：To observe the effect of ropivacaine combined with tramadol in postoperative extradural analgesia （PCEA）. Methods：Fifty patients having undergone operation under extradural anesthesia received extradural cut-over analgesic pump after the operation. The formula of analgesic pump was 0. 894% ropivacaine mesylate,0.8 g tramadol and 3 -5 mg droperidol, which were diluted to 100 ml with normal saline. The pain score, vital signs and complication were observed at 9,12,24 and 36 hour individually. Results：No pain occurred in forty-nine patients;one patient felt satisfied. Thirty patients had phenomena of hypersomnia. No nausea, vomiting,cutaneous pruritus or respiratory repression was observed. Vital signs were steady. Conclusions： The combined therapy of ropivacaine and tramadol is effective and safe for postoperative analgesia, and has little side effect.