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盐酸洛美沙星注射液与利巴韦林注射液配伍稳定性考察
引用本文:李红月,罗朝利,宋畅.盐酸洛美沙星注射液与利巴韦林注射液配伍稳定性考察[J].中国药业,2010,19(14):37-38.
作者姓名:李红月  罗朝利  宋畅
作者单位:中国人民解放军北京军区北戴河疗养院,河北,秦皇岛,066001
摘    要:目的考察盐酸洛美沙星注射液与利巴韦林注射液在25℃和37℃温度下的配伍稳定性。方法采用双波长分光光度法测定配伍液中利巴韦林及盐酸洛美沙星在6 h内的含量及pH变化,同时观察其外观变化。结果配伍液在25℃下0~6 h内外观、pH及含量均无明显变化。结论在上述条件下,利巴韦林注射液可与盐酸洛美沙星注射液配伍。

关 键 词:盐酸洛美沙星  利巴韦林  配伍  稳定性

Compatibility of Lomefloxacin Hydrochloride and Glucose Injection Combined with Ribavirin Injection
Li Hongyue,Luo Chaoli,Song Chang.Compatibility of Lomefloxacin Hydrochloride and Glucose Injection Combined with Ribavirin Injection[J].China Pharmaceuticals,2010,19(14):37-38.
Authors:Li Hongyue  Luo Chaoli  Song Chang
Institution:(Beidaihe Sanatorium of Beijing Military Region,Qinhuangdao,Hebei,China 066001)
Abstract:Objective To investigate the compatibility of Lomefloxacin Hydrochloride and Glucose Injection combined with Ribavirin Injection within 6 h under 25 ℃ and 37 ℃.Methods The content changes of lomefloxacin hydrochloride and ribavirin within 6 h under 25 ℃ and 37 ℃ after combination of both drugs were determined by double wavelength spectrophotometry,at the same time the changes of appearance and pH were observed.Results The significant change of appearance and content in the compatible solution was not observed within 6 h under 25 ℃.Conclusion Under the above-mentioned condition,Lomefloxacin Hydrochloride and Glucose Injection may be used compatibly with Ribavirin Injection.
Keywords:lomefloxacin hydrochloride  ribavirin  compatibility  stability
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