| 氯丙咪嗪治疗强迫性神经症37例临床分析 |
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| 引用本文： | 单怀海,郑瞻培,张磊. 氯丙咪嗪治疗强迫性神经症37例临床分析[J]. 中国新药与临床杂志, 1986, 0(4) |
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| 作者姓名： | 单怀海 郑瞻培 张磊 |
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| 作者单位： | 上海市精神卫生中心，上海市精神卫生中心，上海医科大学精神医学教研室 上海 200030，上海 200030，上海 200032 |
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| 摘 要： | 37例强迫症患者用氯丙咪嗪治疗,按疗效作了随机对照研究。氯丙咪嗪剂量为20-80mg/d,疗程为1mo(月)。结果:有效率76％,对照组用阿米替林有效率为56％。两者在统计学上无明显差异。本文结果提示,氯米咪嗪与阿米替林相比,在治疗强迫症方面疗效无差异。然而,对顽固的强迫行为疗效均欠佳。在强迫症无更有效的药物治疗前,氯丙咪嗪仍是可供选择的药物。
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| 关 键 词： | 强迫症 氯丙咪嗪 阿米替林 强迫观念 强迫性怀疑 强迫计数 强迫性穷思极虑 |
Therapeutic evaluation of chforimipramine in patients suffered from obssession |
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| SHAN Huai-hai,ZHENG Shan-pei. Therapeutic evaluation of chforimipramine in patients suffered from obssession[J]. Chinese Journal of New Drugs and Clinical Remedies, 1986, 0(4) |
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| Authors: | SHAN Huai-hai ZHENG Shan-pei |
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| Abstract: | From December 1983 to February 1985, 37 OPD patients, suffered from obssession, received medical therapy under observation. Among them 28 cases took chlorimipramine, 4-wk trial with daily dose 20-80mg, while the rest amitriptyline as control.Cure and improvement were found to be 76%in the former while 55% in the latter. These figuresthough have no much statical significance, but in the clinical practice, chlorim-pramine is still the drug of choice for obssession-release. |
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| Keywords: | obsession chlorimipra-mine amitriptylin obsessive idea obsessive doubtingj obsessive counting obsessive rumination |
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