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24例胃肠道间质瘤临床病理分析
引用本文:韩静绮.24例胃肠道间质瘤临床病理分析[J].青海医学院学报,2008,29(1):67-69.
作者姓名:韩静绮
作者单位:青海大学附属医院病理科
摘    要:目的探讨胃肠间质瘤的病理组织学和免疫组化学特点及诊断要点。方法对24例胃肠间质瘤进行常规病理及免疫组化CD117、CD34、SMA、S-100染色特点分析。结果24例胃肠间质瘤由梭形细胞和上皮样细胞组成,其中21例CD117和18例CD34标记阳性,阳性表达率分别为87.5%和75%。结论胃肠间质瘤是胃肠常见的间叶性肿瘤,缺乏定向分化。CD117和CD34标记阳性对胃肠间质瘤的诊断具有重要价值。

关 键 词:胃肠间质瘤  免疫组织化学  CD117  CD34
修稿时间:2008年3月4日

HISTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL FEATURES OF GASTROINTESTINAL STROMAL TUMOR
Han Jingqi.HISTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL FEATURES OF GASTROINTESTINAL STROMAL TUMOR[J].Journal of Qinghai Medical College,2008,29(1):67-69.
Authors:Han Jingqi
Institution:Han Jingqi(Department of Pathology,the Affiliated Hospital of Qinghai University)
Abstract:Objective To investigate the pathologic and immunohistochemical features of gastrointestinal stromal tumors(GIST).Methods 24 cases of GIST were studied by routine and immunohistochemistry staining including CD117,CD34,SMA and S-100. Results The GIST consist of two kind of cell types,the spindle and epithelia cells.Among them 21 cases were CD117 positively stained;18 cases were CD34 positively stained.The positive rates were 87.5% and 75% respectively.Conclusion GIST shows no evidence for specific differentiation and the expression of CD117 and CD34 play an important role in the diagnosis of GIST.
Keywords:Gastrointestinal stromal tumors Immunohistis chemistry CD117 CD34
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