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5'-Azacitidine for therapy-related myelodysplastic syndromes after non-Hodgkin lymphoma treatment
Authors:Breccia Massimo  Salaroli Adriano  Loglisci Giuseppina  Martelli Maurizio  D'Elia Gianna Maria  Nanni Mauro  Mauro Francesca Romana  Alimena Giuliana
Affiliation:Department of Cellular Biotechnologies and Hematology, Sapienza University, Via Benevento 6, 00161 Rome, Italy
Abstract:Therapy-related myelodysplastic syndromes are possible complications in patients treated for previous hematologic malignancies. Therapeutic strategies in these type of disorders are still not well defined: azacitidine has been recently approved for the treatment of higher risk myelodysplastic syndromes, but few data are published relating possible efficacy in therapy-related dysplastic disorders. We reported here 4 patients treated with azacitidine for therapy related dysplasia after chemotherapy for non-Hodgkin lymphoma.
Keywords:Azacitine   Therapy-related MDS   Efficacy
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