血液透析治疗肾病综合征急性肾衰竭的效果分析

目的:探讨分析血液透析治疗肾病综合征急性肾衰竭的效果。方法:选取2016年12月~2018年12月本院收治的肾病综合征急性肾衰竭患者64例,依据不同治疗方式分成两组,对照组应用常规治疗,研究组联合应用血液透析。观察比较两组治疗前、后的肾功能指标:血清肌酐(Serum creatinine,Scr)、内生肌酐(endogenous creatinine clearance rate,Ccr)及尿素氮(blood urea nitrogen,BUN)水平变化情况;两组进行为期六个月的随访,观察两组的生存率。结果:治疗前,两组肾功能指标:Scr、Ccr及BUN水平无显著差异(P>0.05),治疗后,研究组Scr及BUN水平显著低于对照组(P<0.05);研究组Ccr水平显著高于对照组(P<0.05);两组均进行为期6个月的随访,研究组在6个月内共有6例(18.8%)发生死亡,对照组共有14例(43.8%)发生死亡,研究组在6个月随访期内的死亡率显著低于对照组(χ^2=5.142,P<0.05)。结论:临床中对肾病综合征急性肾衰竭患者进行治疗的过程中,联合应用血液透析,可显著改善患者的各项肾功能指标,降低患者的死亡比率。

Effect of Hemodialysis on Acute Renal Failure in Nephrotic Syndrome

Objective:To analyze the effect of hemodialysis on acute renal failure with nephrotic syndrome.Methods:Sixty-four patients with acute renal failure with nephrotic syndrome treated in our hospital from December 2016 to December 2018 were selected and divided into two groups according to different treatment methods.The control group was treated with conventional treatment and the research group was treated with hemodialysis.Observe and compare the renal function indicators of the two groups before and after treatment:changes in serum creatinine(Scrum),endogenous creatinine clearance rate(Ccr)and blood urea nitrogen(BUN)levels;During the six-month follow-up,the survival rates of the two groups were observed.Results:Before treatment,there were no significant differences in renal function indicators between the two groups:Scr,Ccr,and BUN levels(P>0.05).After treatment,the levels of Scr and BUN in the study group were significantly higher than those in the control group(P<0.05);Ccr levels in the study group Significantly higher and lower levels were compared with the control group(P<0.05);both groups were followed for a period of 6 months.A total of 6(18.8%)deaths occurred in the study group within 6 months,and a total of 14(43.8%)deaths occurred in the control group.The mortality of the study group during the 6-month follow-up period was significantly lower than that of the control group(χ^2=5.142,P<0.05).Conclusion:The clinical application of hemodialysis in the treatment of patients with acute renal failure with nephrotic syndrome can significantly improve various renal function indexes and reduce the death rate of patients.