Le syndrome métabolique |
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| Affiliation: | 1. Université de Toulouse, université Toulouse III - Paul Sabatier (UPS), Inserm, UMR1297, Institut des maladies métaboliques et cardiovasculaires (I2MC), Toulouse, France;2. Third Faculty of Medicine, Charles University, Franco-Czech Laboratory for Clinical Research on Obesity, Prague, République Tchéque & Université Toulouse III - Paul Sabatier (UPS), Toulouse, France;3. Centre hospitalier universitaire de Toulouse, laboratoire de biochimie, Toulouse, France;4. Institut Universitaire de France (IUF), Paris, France;1. Service des maladies du foie, hôpital Pontchaillou, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France;2. Université Rennes, CHU de Rennes, Inserm CIC1414, 35000 Rennes, France;3. National Reference Center for Hemochromatosis and iron metabolism disorder, CHU de Rennes, 35000 Rennes, France;1. Département nutrition, institut de cardiométabolisme et nutrition, ICAN, Pitié-Salpêtrière hôpital, Assistance publique–Hôpitaux de Paris, 75013 Paris, France;2. Inserm, U1166, UMR_S U1166, nutriomique team 6, Paris, Sorbonne universités, université Pierre-et-Marie-Curie–Paris 6, 75013 Paris, France;1. Unité de formation et de recherche en sciences de la santé, Université de Ouagadougou, Ouagadougou, Burkina Faso;2. Service de médecine interne, Centre hospitalier universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso;3. INSSA, Université polytechnique de Bobo-Dioulasso, Bobo-Dioulasso, Burkina Faso |
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| Abstract: | The metabolic syndrome has a high prevalence in different countries (~ 10% in France). It associates in the same subject central obesity, decrease in HDL cholesterol, increase in plasma triglycérides, glucose intolerance and hypertension. Insulin-resistance is a common featurre even though it has been excluded from the more recent definitions because of the difficulty to assess it in clinical practice. Physiopathology of metabolic syndrome is not univocal. Stress, insulin resistance, central obesity are concerned. Its treatment must associate weight reduction and physical exercise. Fibrates could be of special interest or statins if LDL is elevated. |
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