Tritiation of imipramine and pseudo irreversible analogues 3-Cyanoimipramine and 2-Nitroimipramine at high specific activity |
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| Institution: | 1. Department of Chemistry, University of Texas at El Paso, 500 West University Ave., El Paso, TX 79968, United States;2. Physical and Life Sciences, Lawrence Livermore National Laboratory, 7000 East Ave. L-367, Livermore, CA 94550, United States;3. Nano Carbon Materials Laboratory, Istituto Italiano di Tecnologia, Via Morego 30, Genova 16163, Italy;4. Department of Chemistry and Industrial Chemistry, University of Genova, Via Dodecaneso 31, Genova 16146, Italy;5. Department of Chemistry, Indiana-Purdue University at Fort Wayne, 2101 East Coliseum Boulevard, Fort Wayne, IN 46805, United States;1. Guangzhou Institute of Geochemistry, China Academy of Sciences, Guangzhou 510640, China;2. University of Chinese Academy of Sciences, Beijing 100049, China;1. Interdisciplinary Science Unit, Multidisciplinary Sciences Cluster, Research and Education Faculty, In charge of Science Research Center, Kochi University, Oko Campus, Nankoku, Kochi 783-8505, Japan;2. Graduate School of Integrated Arts and Sciences, Kochi University, Asakura Campus, Kochi 780-8520, Japan;3. Division of Structural and Synthetic Biology, Center for Life Science Technologies, RIKEN Yokohama Campus, Kanagawa 230-0045, Japan |
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| Abstract: | Methods are presented to synthesize and characterize N-methyl-3H] imipramine 3, N-methyl-3H] 3-cyanoimipramine 6 and N-methyl-3H] 2-nitroimipramine 9. |
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