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The fetus with a diaphragmatic hernia
Authors:Michael R. Harrison
Affiliation:(1) Fetal Treatment Program and Division of Pediatric Surgery, University of California, 94143 San Francisco, CA, USa;(2) Department of Surgery, University of California, HSE 585, 94143 San Francisco, CA, USA
Abstract:Prenatal diagnosis of congenital diaphragmatic hernia (CDH) is accurate; current techniques can detect lethal nonpulmonary anomalies and prevent diagnostic errors. Despite optimal conventional therapy, most fetuses with detectable CDH will die in the neonatal period (80% mortality). Polyhydramnios is both a common prenatal marker for CDH and a predictor of poor clinical outcome (only 11% survival). Surgical intervention before birth may be necessary to improve survival of the fetus with CDH and polyhydraminos.
Keywords:Congenital diaphragmatic hernia  Prenatal diagnosis  Fetal surgery
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