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畸精症与染色体异常及反复流产或死胎关系的研究
引用本文:曾设民,朱文兵,卢光. 畸精症与染色体异常及反复流产或死胎关系的研究[J]. 中南大学学报(医学版), 1995, 0(3)
作者姓名:曾设民  朱文兵  卢光
作者单位:Human Reproductue Engineering Laboratory,Hunan Medical University
摘    要:对46例畸精症患者染色体及其配偶反复流产、死胎的情况进行了分析,发现1例常染色体易位,11例伴有大Y染色体,其大Y发生率明显高于正常人群。伴有大Y染色体的畸精症患者,其配偶流产或死胎的频率高于染色体正常的患者。表明畸精症、流产和兄胎的发生与Y染色体的变异有关。

关 键 词:精子;染色体异常;流产,习惯性;胎死

STUDY ON RELATIONSHIP OF TERATOZOOSPERMIA BETWEEN CHROMOSOMAL ABNORMALITY AND RECURRENT ABORTIONS OR RETAL DEATHS
Zeng Shemin, Zhu Wenbing, Lu Guangxiu. STUDY ON RELATIONSHIP OF TERATOZOOSPERMIA BETWEEN CHROMOSOMAL ABNORMALITY AND RECURRENT ABORTIONS OR RETAL DEATHS[J]. Journal of Central South University. Medical sciences, 1995, 0(3)
Authors:Zeng Shemin   Zhu Wenbing   Lu Guangxiu
Abstract:his paper analyzed chromosome in 46 teratozoospermic males and incidence of recur-rent abortions or fetal deaths of their wives.One case of balanced autosomal translocationand eleven cases of large Y were found.Incidence of large Y in teratozoospermia(23.91%)was higher than that in normal population of China(11.18%).The percent of recurrentabortions or fetal deaths in teratozoospermic males with large Y was higher than that ofnormal chromosome group(P<0.05).It is speculated that the incidence of teratozoospermiaand recurrent abortions or fetal deaths were related to heterochromatic variants like largeY,and the variants likd large Y could be one of the causes of teratozoospermia and play animportant role in recurrent abortions or fetal deaths related to teratozoospermia.
Keywords:spermatozoa  abnormalities  chromosome abnormalities  abortion  ha-bitual  fetal death  
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