颅内转移瘤的诊治分析

目的:探讨颅内转移瘤的最佳治疗方法.方法:回顾性分析我院近4年来对颅内转移瘤的治疗,治疗方法包括开颅手术切除、开颅手术加全脑放射治疗、X刀加全脑放射治疗.结果:开颅手术治疗与开颅手术加全脑放射治疗两者的中位生存期比较有统计学意义,开颅手术加全脑放射治疗与X刀加全脑放射治疗两者的中位生存期比较没有统计学意义.结论:对于颅内转移瘤,根据患者的具体情况,采取不同的治疗方案:一般情况好的患者,开颅手术加全脑放射治疗优于单纯开颅手术治疗,直径不超过3～4cm的单发或多发颅内转移瘤,可以行开颅手术加全脑放射治疗或X刀加全脑放射治疗.

Management of Intracranial Metastases

Objective: To evaluate the results of the treatment for patients with intracranial metastatic tumors, and find out the best treatment method for them. Methods: Patients with intracranial metastatic tumors were grouped into three categories: surgery, surgery with whole brain radiation therapy(WBRT) ,X - Knife with WBRT. Results: The medial survival time of surgery with WBRTwas significantly longer than that of surgery only, There were no significant difference in the median survival time between surgery with WBRT and X -Knife with WBRT.Conclusion: The most appropriate intervention for the individual patient was dependent on the patient' s characteristics . Surgery with WBRT was superior to surgery for the treatment of brain metastasis in patients with good neurological condition. Surgery with WBRT or X - Knife with WBRT were suitable for patients with lesion's diameter didn' t exceed 3-4 cm.