肺癌淋巴结转移规律的研究

目的：探讨肺癌淋巴结的转移规律。方法：对2004年1月～2006年10月收治的396例肺癌同侧肺门、叶间及纵隔淋巴结广泛廓清手术患者的临床资料进行回顾性分析，比较不同的临床分期（T1、T2、T3、T4）、病理类型（鳞癌、腺癌、其他）、病变部位（中央型、周围型）的患者淋巴结转移率。结果：396例中195例（49．3％）存在N1或（和）N2淋巴结转移，其中单纯N1淋巴结转移44例（11．1％），N2淋巴结转移151例（38．1％）；单因素分析结果表明，原发肿瘤分期、原发部位和病理类型均会对肺癌的淋巴结转移率及转移部位有影响（P〈0．01）。结论：肺癌容易发生淋巴结转移，淋巴结转移与原发肿瘤分期（T）、原发部位和病理类型均有密切相关。为达到根治目的，提倡纵隔和肺门淋巴结系统清扫。

A study on metastasis rules of lymph node in patents with lung cancer

Objective:To investigate the clinical rule of lymph nodes metastasis in primary lung cancer.Methods:Three hundred and ninty-six patients with lung cancer underwent lobectomy or pneumonectomy during Jan.2004 to Oct.2006 in our hospital were retrospectively analyzed.Totally 2 713 lymph nodes were removed and checked up pathologically.Results:Lymph nodes with metastases were confirmed in 195 out of the 396 cases,and the metastasis ratio was 49.3%,and among them 44 patients suffered N1 lesion,with the ratio of 11.1%.Univariate analysis showed that the predictors of metastases rate of lymph nodes were T stage,initial location and pathological type.Conclusion:Lymph node metastasis in lung cancer is common and related to multiple factors.In order to obtain radical cure,both mediastinal and hilar lymph nodes should he removed.