螺旋藻加转移因子辅助治疗复治肺结核疗效观察

目的　观察螺旋藻加转移因子辅助治疗复治肺结核疗效。方法 将 192例涂阳复治患者随机分为治疗组 (100例)和对照组 (92例)。 2组化疗方案相同,治疗组在化疗同时加螺旋藻胶囊 3粒口服,3次/d；转移因子 3mg,皮下注射,2次 /周。结果 9月末痰菌阴转率,治疗组 92%,对照组73.9%(P＜0.01)；X线胸片病灶吸收好转率和空洞闭合率治疗组分别为 88%和 76%,对照组分别为 73.9%和 5 9.8%(P＜0.05)。治疗组不良反应发生率明显低于对照组 (分别为 6%和 26%,P＜0.01)。结论 两药联合辅助治疗复治肺结核有效,并可降低抗结核药物不良反应的发生率。

Observation of supplementary treatment effect of spirin and transfer factor for treating reteated pulmonary tuberculosis

Objective To observe the supplementary treatment effect for pulmonary tuberculosis treated of spirin and transfer factor.Methods One hundred and ninety two patients were divided into two groups: therapy group with 100 cases, control group with 92 cases. The therapy group received chemical therapy and three spirin capsules, three times a day, transfer factor 3mg, imjection(H) twice a week.Results At the end of 9 months, the sputum conversion rate was 92%(in therapy group), 73.9%(in control group), P<0.01. The foci absorption was 88%(therapy group) and 76%(control group), Cavity cloce up was 73.9% (ther-apy group), 59.8%(control group),P<0.05. The therapy group's side effect rate (6%) was lower than that of control group(26%), P<0.01. Conclusion The supplementary treatment effect of spirin and transfer factor for treating retreated pulmonary tuberculosis was obvious. Especially for reducing side effect of antituberculosis.