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固尔苏联合CPAP治疗新生儿呼吸窘迫综合征的疗效
引用本文:郦红艳,李晖.固尔苏联合CPAP治疗新生儿呼吸窘迫综合征的疗效[J].中国医药导报,2011,8(23):72-73.
作者姓名:郦红艳  李晖
作者单位:江苏省镇江市第四人民医院(妇幼保健院)儿科,江苏镇江,212001
摘    要:目的:探讨固尔苏联合鼻塞式持续呼吸道正压通气(CPAP)治疗新生儿呼吸窘迫综合征(NRDS)的疗效。方法:对本院29例确诊为NRDS的病例早期给予CPAP,并联合固尔苏治疗。观察治疗前后临床表现、胸片及血气指标的变化。结果:29例患儿经CPAP及固尔苏治疗后呼吸困难明显改善,X线胸片明显好转。患儿血气分析显示治疗前pH为(7.22±0.07),治疗后6—24h为(7.37±0.05),治疗后48h为(7.40±0.05);治疗前Pa02为(5.65±1.74)kPa,治疗后6—24h为(10.73±3.04)kPa,治疗后48h为(13.07±3.65)kPa;治疗前PaC02为(7.46±1.46)kPa,治疗后6—24h为(5.40±1.17)kPa,治疗后48h为(5.40±0.51)kPa;与治疗前相比,治疗后6~24h、治疗后48h的pH、PaO2、PaCO2显著改善,差异有统计学意义(P〈0.05)。结论:早期给予CPAP联合固尔苏治疗NRDS疗效显著,并发症少。

关 键 词:新生儿呼吸窘迫综合征  肺表面活性物质  正压通气

Therapeutic effect of Curosurf combined with CPAP in treatment of neonatal respiratory distress syndrome
LI Hongyan,LI Hui.Therapeutic effect of Curosurf combined with CPAP in treatment of neonatal respiratory distress syndrome[J].China Medical Herald,2011,8(23):72-73.
Authors:LI Hongyan  LI Hui
Institution:Department of Pediatrics,the Fourth People′s Hospital(MCH) of Zhenjiang City,Jiangsu Province,Zhenjiang 212001,China
Abstract:Objective: To investigate the therapeutic effect of Curosurf combined with continuous postitive airway pressure(CPAP) in treatment of neonatal respiratory distress syndrome(NRDS).Methods: 29 infants with NRDS were supported with CPAP and in combination with early treatment of Curosurf,the clinical manifestation,X-ray and blood gas were com-pared between pre-treatment and post-treatment.Results: Dyspnea was relieved and X-ray was imporved markedly after treatment with Curosurf combined with CPAP.The power of...
Keywords:Respiratory distress syndrome of newborn  Pulmonary surfactant  Continuous postitive airway pressure  
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