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孟鲁斯特治疗支气管哮喘的临床观察
引用本文:罗艺,张浒.孟鲁斯特治疗支气管哮喘的临床观察[J].中国医药导报,2011,8(16):87-87.
作者姓名:罗艺  张浒
作者单位:广东省高州市中医院内科,广东高州,525200
摘    要:目的:观察孟鲁斯特对支气管哮喘的疗效。方法:将40例支气管哮喘患者随机分为治疗组和对照组,各40例,治疗组在对照组的基础上应用孟鲁斯特10 mg/d,对照组予吸入糖皮质激素(ICS)布地奈德喷雾剂和长效β2受体激动剂(LABA)福莫特罗喷雾剂,急性严重发作时加用速效吸入β2受体激动剂和吸氧治疗。比较两组哮喘缓解情况和发作的频率及总有效率。结果:治疗组总有效率为90.0%(36/40例)高于对照组85.0%(34/40例),差异有统计学意义(P〈0.05)。结论:孟鲁斯特对支气管哮喘的疗效显著,安全性好,值得推广应用。

关 键 词:孟鲁斯特  支气管哮喘  临床疗效

Clinical observation of bronchial asthma treated by Montelukast
LUO Yi,ZHANG Hu.Clinical observation of bronchial asthma treated by Montelukast[J].China Medical Herald,2011,8(16):87-87.
Authors:LUO Yi  ZHANG Hu
Institution:LUO Yi,ZHANG Hu Department of Medicine,Traditional Chinese Medicine Hospital of Gaozhou City,Guangdong Province,Gaozhou 525200,China
Abstract:Objective: To observe the long-term therapeutic effect of Montelukast on bronchial asthma.Methods: Forty patients with bronchial asthma were enrolled and divided into treatment group and control group randomly.The patients in control group were treated with inhaled corticosteroid(ICS)(10 mg/d) and long acting β2-agonist(LABA),and those in treatment group were added Montelukast.Both of the groups were inhaled short-acting β2-agonists and given oxygen therapy.Results: The effective rate of treatment group was higher than that of control group(90.0% vs 85.0%,P0.05).Conclusion: Montelukast is an effective and safe treatment method to bronchial asthma and worthy to clinical application.
Keywords:Montelukast  Bronchial asthma  Clinical efficacy  
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