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Advanced paternal age and reproductive outcome
Authors:Wiener-Megnazi Zofnat  Auslender Ron  Dirnfeld Martha
Affiliation:Fertility and IVF Unit, Department of Obstetrics and Gynecology, Carmel Medical Center, the Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.
Abstract:Women have been increasingly delaying the start of motherhood in recent decades. The same trend is seen also for men. The influence of maternal age on fertility, chromosomal anomalies, pregnancy complications, and impaired perinatal and post-natal outcome of offspring, has been thoroughly investigated, and these aspects are clinically applied during fertility and pregestational counseling. Male aging and reproductive outcome has gained relatively less attention. The purpose of this review is to evaluate updated and relevant literature on the effect of paternal age on reproductive outcome.
Keywords:ART outcomes   fertility   male aging   paternal age   reproductive outcome
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