Mumps outbreak in a highly vaccinated student population,The Netherlands, 2004 |
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| Authors: | Heinrich J Brockhoff Liesbeth Mollema Gerard JB Sonder Cees A Postema Robert S van Binnendijk Robert HG Kohl Hester E de Melker Susan JM Hahné |
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| Institution: | 1. Department Infectious Disease, Municipal Health Service, The Hague, The Netherlands;2. Centre for Infectious Disease Control Netherlands, RIVM, Bilthoven, The Netherlands;3. Department Infectious Disease, Municipal Health Service, Amsterdam, The Netherlands;4. Academic Medical Center, Department of Internal Medicine, Division of Infectious Diseases, Tropical Medicine and AIDS, Amsterdam, The Netherlands;5. Netherlands Forensic Institute, The Hague, The Netherlands |
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| Abstract: | In September 2004 a mumps outbreak occurred at an international hotel school in The Netherlands. We investigated this outbreak to identify risk factors for mumps. There were 105 mumps cases (overall mumps attack rate (AR) 12% (95% CI: 10–15%)). The AR for Dutch vaccinated and unvaccinated participants was 12% (95% CI: 10–15%) and 15% (95% CI: 3–42%), respectively. Independent risk factor was mumps contact. Explanations for the relatively high AR among vaccinated participants include primary vaccine failure, waning immunity and incomplete vaccine-induced immunity in the context of high mumps virus exposure in a school party and a crowded boarding school. |
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| Keywords: | Mumps outbreak Highly vaccinated school Risk factors |
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