冠心病并存血糖异常患者冠状动脉病变特点的分析

目的探讨冠心病并存血糖异常患者冠状动脉病变的特点。方法对2006年1月至2006年6月在山西医科大学第一医院行冠状动脉造影术确诊为冠心病的136例患者进行回顾性分析,分为两组:血糖异常组64例,血糖正常组72例,对两组患者的临床特点和冠状动脉造影结果进行对比分析。结果两组资料在年龄、性别、吸烟史、体重指数、高密度脂蛋白胆固醇、心肌梗死发生率和冠状动脉病变的部位方面的比较均无显著差异(P>0.05)。血糖异常组高血压、胆固醇、甘油三酯、低密度脂蛋白胆固醇以及载脂蛋白B均高于血糖正常组(P<0.05);血糖异常组冠状动脉病变的狭窄程度重,中度、重度狭窄、多支病变和弥漫性病变发生率显著增高(P<0.05)。结论冠心病伴血糖异常的患者多同时伴有冠心病的其他危险因素,其冠状动脉病变复杂,病变程度严重,多支病变和弥漫性病变增多。

Features of coronary artery lesion in coronary heart disease patients with pathoglycemia

Objective To investigate the features of coronary artery lesion in coronary heart disease (CHD) patients with pathoglycemia. Methods A total of 136 CHD patients diagnosed by coronary angiography (CAG) in the First Affiliated Hospital of Shanyi Medical University from January 2004 to June 2004 were analyzed retrospectively. Patients were divided into two groups: 64 cases with pathoglycemia (pathoglycemia group) and 72 cases with normal glucose level (control group). Clinical characteristics and CAG results were recorded and compared between the two groups. Results There were no differences in age, sex, smoking, body mass index, high density lipoprotein cholesterol, incidence of myocardial infarction and locus of coronary artery lesion between the two groups (P>0.05). The incidence of hypertension, as well as the level of cholesterol, triglyceride, low density lipoprotein cholesterol and apolipoprotein B in the pathoglycemia group were much higher than those in the control group (P<0.05). Compared with the control group, patients in the pathoglycemia group suffered more moderate and severe stenosis of coronary artery, mult-vessel lesions and diffuse vessel lesions (P<0.05). Conclusions CHD patients with pathoglycemia prone to have simultaneously many other risks of CHD, their coronary lesions are more severe and complicated many patients have mult-vessel lesions and diffuse vessel lesions.