| 尼克酰胺腺嘌呤二核苷酸磷酸氧化酶与心血管疾病关系的研究进展 |
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| 引用本文： | 刘保逸,何青. 尼克酰胺腺嘌呤二核苷酸磷酸氧化酶与心血管疾病关系的研究进展[J]. 中国心血管杂志, 2007, 12(4): 303-306 |
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| 作者姓名： | 刘保逸 何青 |
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| 作者单位： | 1. 中国协和医科大学研究生院,北京,100730;北京医院心内科,北京,100730
2. 北京医院心内科,北京,100730 |
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| 摘 要： | 活性氧的增加与心血管疾病密切相关,而产生活性氧的主要酶体是尼克酰胺腺嘌呤二核苷酸氧化酶(NADPH氧化酶)。NADPH氧化酶对动脉粥样硬化、高血压、心力衰竭的发生发展起着重要的作用;而心房颤动又可引起NADPH氧化酶的增加。
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| 关 键 词： | 尼克酰胺腺嘌呤二核苷酸氧化酶 心血管疾病 |
| 文章编号： | 1007-5410（2007）04-0303-04 |
| 修稿时间： | 2007-06-22 |
Relation between nicotinamide adenine dinucleotide phosphate(NADPH) Oxidase and cardiovascular disease |
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| LIU Bao-yi,HE Qing. Relation between nicotinamide adenine dinucleotide phosphate(NADPH) Oxidase and cardiovascular disease[J]. Chinese Journal of Cardiovascular Medicine, 2007, 12(4): 303-306 |
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| Authors: | LIU Bao-yi HE Qing |
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| Affiliation: | 1.Graduate School of Peking Union Medical College,Beijing 100730;2.Department of Cardiology,Beijing Hospital,Beijing 100730,China |
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| Abstract: | Overproduction of reactive oxygen species(ROS) under pathophysiologic condition is crucial in the development of cardiovascular diseases.The major source of ROS is from NADPH Oxidase(NOX).NOX plays an important role in the progress of atherosclerosis,hypertension and heart failure;on the other hand,it can be increased by atrial fibrillation. |
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| Keywords: | NADPH Oxidase Cardiovascular disease |
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