| 绒毛膜促性腺激素对人胃腺癌细胞增殖的影响 |
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| 引用本文： | 张群洲,陈曼玲,李蓉晖,廖英. 绒毛膜促性腺激素对人胃腺癌细胞增殖的影响[J]. 四川大学学报(医学版), 2003, 34(4): 678-679 |
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| 作者姓名： | 张群洲 陈曼玲 李蓉晖 廖英 |
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| 作者单位： | 四川大学华西基础医学与法医学院,生物化学与分子生物学教研室,成都,610041 |
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| 摘 要： | 目的 探讨人绒毛膜促性腺激素(hCG)对人胃腺癌SGC-7901细胞增殖生长的影响。方法用MTT法检测细胞生长率及存活率。结果 hCG在10^11～10^-8mol／L范围内，对胃腺癌细胞的生长具有促进作用，但无明显的时间依较关系。结论 hCG对胃腺癌细胞的生长具有一定的促进作用，提示hCG在胃腺癌的发生与发展中起了一定的作用。
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| 关 键 词： | 绒毛膜促性腺激素 胃腺癌 细胞增殖 MTT法 |
| 修稿时间： | 2002-05-08 |
Studies on the Effects of Human Chorionic Gonadotropin on the Growth of Human Gastric Adenocarcinoma Cells |
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| Zhang Qunzhou,Liao Ying,Li Ronghui,Chen Manling. Studies on the Effects of Human Chorionic Gonadotropin on the Growth of Human Gastric Adenocarcinoma Cells[J]. Journal of Sichuan University. Medical science edition, 2003, 34(4): 678-679 |
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| Authors: | Zhang Qunzhou Liao Ying Li Ronghui Chen Manling |
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| Affiliation: | Department of Biochemistry & Molecular Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China. |
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| Abstract: | Objective To investigate the effects of human gastric chorionic gonadotropin (hCG) on the growth of human gastric adenocarcinoma cells. Methods MTT reduction assay was used to determine the cell growth and survival rates. Results Within the concentration range of 10 -11 10 -6 mol/L, hCG could slightly stimulate the growth of gastric cancer cells but in a obvious time dependent manner. Conclusion hCG has slightly stimulatory effect on the proliferation gastric adenocarcinoma cells,suggestion that hCG may possibly play a role in regulation the tumorigenesis of gastric cancer. |
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| Keywords: | Human chorionic gonadotropin Gastric adenocarcinoma Cell growth |
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