祛痰化瘀饮对老年糖尿病性冠心病患者血脂代谢的影响

目的观察祛痰化瘀饮对老年糖尿病性冠心病患者血脂代谢的影响。方法将70例老年糖尿病冠心病合并高脂血症患者随机分为对照组和治疗组两组,每组35例。对照组给予降糖、降脂和冠心病常用西药治疗,治疗组在对照组治疗基础上加用祛痰化瘀饮。观察治疗前后两组患者中医证候变化及血清总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）水平,并判定临床疗效。结果完成病例64例,每组各32例。治疗组总有效率90.6%,对照组总有效率81.3%,两组总有效率比较,差异有统计学意义（P〈0.05）。治疗组治疗后TC、TG较对照组治疗后均明显降低,差异具有统计学意义（P〈0.05）。治疗组治疗后中医证候积分较治疗前明显下降（P〈0.01）,且与对照组治疗后比较,差异有统计学意义（P〈0.05）。结论祛痰化瘀饮具有改善老年糖尿病性冠心病血脂谱及症状的作用。

Impacts of Qutan Huayu Yin on Blood Lipid Metabolism in the Patients with Senile Diabetic Coronary Heart Disease

Objective To observe the impacts of qutan huayu yin on blood lipid metabolism in the patients with senile diabetic coronary heart disease.Methods 70 cases of senile diabetic coronary heart disease combined with hyperlipidmia were randomly divided into a control group and a treatment group,35 cases in each group.In control group,the conventional western medication was applied for anti-glucose,anti-lipid and coronary heart disease.In treatment group,on the basis of the treatment as control group,qutan huayu yin was added.The changes of syndromes in Chinese medicine,serum total cholesterol（TC）,triglycerides（TG）,low-density lipoprotein cholesterol（LDL-C）and high-density lipoprotein cholesterol（HDL-C）levels were observed before and after treatment in two groups.The clinical efficacy was evaluated.Results 64 cases were fulfilled the observation,32 cases in each group.The total effective rate was 90.6% in treatment group and was 81.3% in control group,presenting significant statistical difference in comparison（P0.05）.In treatment group,after treatment,TC and TG levels reduced apparently as compared with those in control group,indicating significant statistical difference（P0.05）.Syndrome score of Chinese medicine reduced apparently as compared with that before treatment in treatment group（P0.01）.It was significantly different in statistics as compared with control group（P0.05）.Conclusion Qutan huayu yin improves blood lipid spectrum and relieves the symptoms of Chinese medicine in the patients with senile diabetic coronary heart disease.