甲苯胺红不加热血清试验和梅毒螺旋体抗体明胶颗粒凝集试验在梅毒诊治中的应用

目的探讨梅毒血清学试验甲苯胺红不加热血清试验（TRUST）与梅毒螺旋体抗体明胶颗粒凝集试验（TPPA）在梅毒诊断及治疗中的作用。方法对210例疑为梅毒患者及200例健康体检者的血清作TRUST试验和TPPA试验，并对其结果进行比较分析。结果200例健康体检者中，TRUST试验和TPPA试验均为阴性;210例疑为梅毒患者中，TRUST试验阳性的有192例，TPPA试验阳性的有200例，两者均为阳性的有182例，TPPA试验100%符合临床诊断，TRUST试验有一定的假阳性和假阴性。结论TPPA对TRUST试验阳性病例和疑为梅毒患者有排除和证实作用，而TRUST试验则可作为梅毒患者筛选和疗效观察的一项指标。

Application of Toluidine Red Unheated Serum Test and Treponemal Pallidum Particle Agglutination for Diagnosis and Treatment of Syphilis

Objective To study the clinical application of Toluidine Red Unheated Serum Test(TRUST) and Treponemal Pallidum Particle Agglutination(TPPA) for diagnosis and treatment of syphilis.Method TRUST and TPPA were performed for 210 suspected patients with syphilis and 200 healthy individuals. Results As for the 210 suspected patients,192 were positive for TRUST and 200 positive for TPPA and 182 of them were positive for both.None of the 200 controls were positive for TRUST or TPPA.The results of TPPA were coincidental to clinical diagnosis.However,the results of TRUST didnt completely conform to clinical diagnosis.Conclusion The TRUST can be used to screen out the suspected patients with syphilis.The TPPA could be used for clinical diagnose with syphilis.