| 酸中毒早产儿脑损伤的危险因素分析 |
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| 引用本文： | 刘振球,余加林,王建辉. 酸中毒早产儿脑损伤的危险因素分析[J]. 重庆医学, 2009, 38(14) |
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| 作者姓名： | 刘振球 余加林 王建辉 |
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| 作者单位： | 重庆医科大学附属儿童医院新生儿科,400014;重庆医科大学附属儿童医院新生儿科,400014;重庆医科大学附属儿童医院新生儿科,400014 |
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| 摘 要： | 目的 探讨围产期低血糖对伴酸中毒早产儿脑损伤的影响.方法 回顾性分析153例伴酸中毒(pH＜7.30)早产儿病历资料.结果 116例(75.8%)患儿出现不同程度的脑损伤表现,包括10倒(8.6%)存在缺血缺氧性脑病(HIE)而死亡,106例(87.1%)为中到重度HIE.153例中有107例(70.0%)存在低血糖.107例低血糖中的102例(87.9%)及46例正常血糖中的14例(12.1%)出现脑损伤表现(OR=46.6,P＜0.01).通过ROC分析方法时出生体重、动脉血pH值、5min Apgar评分、乳酸进行界点确定,分别为1775g、7.15、6、6.15mmol/L.结论 围产期低血糖是造成早产儿脑损伤的重要危险因素,尤其同时存在新生儿窒息需要心肺复苏及伴有酸中毒时,脑损伤的风险明显增加.
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| 关 键 词： | 早产儿 低血糖 酸中毒 脑损伤 |
Multiple-factor analysis of hypoglycemia on brain injury in preterm infants with acidosis |
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| LIU Zhen-qiu,YU Jia-lin,WANG Jian-hui. Multiple-factor analysis of hypoglycemia on brain injury in preterm infants with acidosis[J]. Chongqing Medical Journal, 2009, 38(14) |
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| Authors: | LIU Zhen-qiu YU Jia-lin WANG Jian-hui |
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| Abstract: | Objective To explore the effect of perinatal hypoglycemia on brain injury in preterm infants with acidosis.Methods One hundred and fifty-three cases of preterm infants with acidosis were analysed retrospectively.Results One hundred and sixteen preterm infants(75.8%) were manifested with different extend of brain injury,including 10(8.6%) with severe hypoxic-ischemic encephalopathy(HIE) who died,101(87.1%) with moderate to severe HIE and 5(4.3%)with seizures.Of all the infants,107(70.0%)were diagnosed hypogl... |
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| Keywords: | preterm infant hypoglycemia acidosis brain injury |
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