Synthesis of a heparinized poly(organophosphazene) |
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| Authors: | Thomas X. Neenan Harry R. Allcock |
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| Affiliation: | Department of Chemistry, The Pennsylvania State University, University Park, Pennyslvania 16802, USA |
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| Abstract: | The synthesis of a new potential anti-thrombogenic polymer is described. Limited halogenation of an aryloxysubstituted polyphosphazene, followed by quaternization with triethylamine yielded a polymer capable of forming polyelectrolyte complexes with sodium heparin. The results of preliminary clotting tests with bovine blood are presented. |
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| Keywords: | Polymer heparin poly (organophosphazene) blood compatibility |
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