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再灌注性心律失常的电生理实验研究
引用本文:尹红,张薇,王子法,高德恩,张运,刘旭,张振杰.再灌注性心律失常的电生理实验研究[J].中国循环杂志,1993(1).
作者姓名:尹红  张薇  王子法  高德恩  张运  刘旭  张振杰
作者单位:山东医科大学附属医院心内科 (尹红,张薇,王子法,高德恩,张运,刘旭),莱芜市城关镇医院内科(张振杰)
摘    要:本文在20只犬实验性缺血—再灌注时。应用心电活动三维标测系统。对心肌多层次(双极针电极)进行电生理检查。结果表明,27%的非持续性室性心动过速(下简称室速)起源于缺血区的心内膜下,并与室速前—窦性心搏在缺血区发生延迟激动有关,支持壁内折返机制;73%的非持续性室速起源于再灌注的正常交界处的心内膜下,支持非折返机制,导致心室颤动(下简称室颤)的室速也起源于再灌注的正常交界处的心内膜下,支持非折返机制。上述结果支持再灌注性心律失常的多种机制学说。

关 键 词:缺血一再灌注  心律失常  

ELECTROPHYSIOLOGIC STUDY OF REPERFUSION ARRHYTHMIAS
Yin Hong,Zhang Wei,Wang Zi-Fa,et al..ELECTROPHYSIOLOGIC STUDY OF REPERFUSION ARRHYTHMIAS[J].Chinese Circulation Journal,1993(1).
Authors:Yin Hong  Zhang Wei  Wang Zi-Fa  
Institution:Yin Hong,Zhang Wei,Wang Zi-Fa,et al. Affiliated Hospital of Shandong Medical University,Jinan
Abstract:Twenty dogs of experimental ischemic reperfusion were studied with a three-dimensional mapping system of cardiac electric activity and multiple-level myocardial recordings by bipolar plunge-needle electrodes. 27% of the nonsustained ventricular tachycardia (NSVT) of intramural reentry occurred in the ischemic subendocardium by the side of delayed myocardial activation in the ischemic zone from the preceding sinus beat. 3% of the NSVT occurred in the subendocardium of the normal zone adjacent to the reperfused zone via a mechanism not involving reentry, so did VT leading to ventricular fibrillation. The results support that multiple mechanisms are involved in reperfusion arrhythmias.
Keywords:Ischemic reperfusion  Arrhythmias
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