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Uncommon Type of Meningiomas with Conspicuous Plasmo-lymphocytic Infiltration: An Immunohistochemical and Histochemical Study
Authors:Takaaki Ohmori  Ryo Tabei  Keiji Fukui  Kazuhiko Sadamoto  Saburo Sakaki
Affiliation:Second Department of Pathology, Ehime University School of Medicine, Ehime.;Department of Neurosurgery, Washo-kai Sadamoto Hospital, Ehime.;Department of Neurosurgery, Ehime University School of Medicine, Ehime.
Abstract:Two cases of meningioma revealing conspicuous plasmo lymphocytic tissue and hyalinized fibrous tissue components are reported. Histopathological examination of the plasmo lymphocytic infiltration was performed. Both lesions showed polyclonality of plasma cells as revealed by positive reactions for 1gG and paraimmunoglobulin χ- and λ light chains, and amyloid infiltration into the fibrous stroma and blood vessel walls. The histochemical and immunohistochemical characteristics of the lesion in relation to its etiology are briefly discussed. Acta Pathol. Jpn. 32: 190∼194, 1989.
Keywords:Meningioma    Plasma cell    Hyperglobulinemia    Amyloid    Immunohistochemistry
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