| 共载同源成分葛根素与大豆苷元的聚合物混合胶束的制备及表征 |
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| 引用本文： | 朱卫丰,况文亮,李文栋,丁权,周志炜,吴文婷,管咏梅.共载同源成分葛根素与大豆苷元的聚合物混合胶束的制备及表征[J].中草药,2022,53(4):1004-1012. |
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| 作者姓名： | 朱卫丰 况文亮 李文栋 丁权 周志炜 吴文婷 管咏梅 |
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| 作者单位： | 江西中医药大学 现代中药制剂教育部重点实验室, 江西 南昌 330004 |
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| 基金项目： | 国家重点研发计划项目（2017YFC1702904）；江西省自然科学基金项目（20212BAB216013） |
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| 摘 要： | 目的 鉴于葛根黄酮类成分间溶解性与渗透性的自调节作用,以泊洛沙姆407(Pluronic F127,F127)和15-羟基硬脂酸聚乙二醇脂(Solutol HS15)为载体材料制备共载葛根素与大豆苷元的聚合物混合胶束(puerarin and daidzein co-delivery polymer mixed mic...
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| 关 键 词： | 葛根素 大豆苷元 共载 聚合物混合胶束 冻干 自调节 同源成分 薄膜水化法 体外透析法 成型性 |
| 收稿时间： | 2021/10/24 0:00:00 |
Preparation and characterization of polymer mixed micelles co-loaded with homologous components of puerarin and daidzein |
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| ZHU Wei-feng,KUANG Wen-liang,LI Wen-dong,DING Quan,ZHOU Zhi-wei,WU Wen-ting,GUAN Yong-mei.Preparation and characterization of polymer mixed micelles co-loaded with homologous components of puerarin and daidzein[J].Chinese Traditional and Herbal Drugs,2022,53(4):1004-1012. |
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| Authors: | ZHU Wei-feng KUANG Wen-liang LI Wen-dong DING Quan ZHOU Zhi-wei WU Wen-ting GUAN Yong-mei |
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| Institution: | Key laboratory of Modern Chinese Materia Medica Preparation of Ministry of Education, Jiangxi University of Chinese Medicine, Nanchang 330004, China |
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| Abstract: | |
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| Keywords: | puerarin daidzein co-delivery polymer mixed micelles lyophilized powder self-adjusting homologous components thin-film hydration method in vitro dialysis formability |
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