| 小胶质细胞与脑缺血 |
| |
| 引用本文： | 宋玉成,刘永海.小胶质细胞与脑缺血[J].国际脑血管病杂志,2006,14(6):456-458. |
| |
| 作者姓名： | 宋玉成 刘永海 |
| |
| 作者单位： | 221002,徐州医学院附属医院神经内科 |
| |
| 摘 要： | 小胶质细胞是脑内的主要免疫效应细胞,在神经元的生理活动中起支持、营养、保护和修复等重要功能。脑缺血后,小胶质细胞迅速活化和增殖,发挥巨噬细胞的吞噬效应,并通过产生神经毒性分子和神经营养因子发挥双重作用。因此,研究小胶质细胞与脑缺血的关系,充分发挥其保护功能,降低其损害作用,将有助于提高缺血性脑损伤的救治效果。
|
| 关 键 词： | 小胶质细胞 脑缺血 |
| 收稿时间： | 2006-01-15 |
| 修稿时间： | 2006-03-22 |
Microglia and Cerebral Ischemia |
| |
| Yu-Cheng Song,Yong-Hai Liu.Microglia and Cerebral Ischemia[J].International Journal of Cerebrovascular Diseases,2006,14(6):456-458. |
| |
| Authors: | Yu-Cheng Song Yong-Hai Liu |
| |
| Institution: | Department of Neurology, the Affiliated Hospital of Xuzhou Medicol College, Xuzhou 221002, China |
| |
| Abstract: | Microglia is the principal immune effector cell in brain. It plays some important roles in support, nutrition, protection, and repair in the physiological activities of neuron. Microglia can be quickly activated, which may proliferate after cerebral ischemia, and promote phagocytosis of macrophage. It exerts dual effects by producing neurotoxic molecules and neurotrophic factors. Therefore, to study the relationship between microglia and cerebral ischemia, give full play to its protective functions and reduce its damage will help to improve the therapeutic effects of cerebral ischemic injury. |
| |
| Keywords: | microglia cerebral ischemia |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
