伸展细胞型室管膜瘤的临床病理特点

目的：观察一少见的特殊类型室管膜瘤的临床病理特点,拟译名为伸展细胞型室管膜瘤。方法：复习3例此型的临床病理和免疫组化资料及有关文献。结果：3例肿瘤均位于脊髓内。它们的临床表现和放射影像学与室管膜瘤其他类型表现相同,病理形态学上,瘤细胞呈现双极的长梭形胶质细胞,形成不典型的血管周菊形团,GFAP、EMA弱阳性,而vimentin强阳性,而可与星形细胞瘤及神经鞘瘤相鉴别,其预后与其他类型室管膜瘤相类似。结论：由于肿瘤由双极、长梭形细胞组成。及tanycyte来源于tanyos有stretch伸出展开之意,“tanycytic ependymona ”以译成“伸展细胞型室管膜瘤”为妥。

Clinicopathological featues of tanycytic ependymomas

Purpose To investigate the clinicopathological features of a rare type of ependymoma, termed tanycytic ependymoma. Methods The clinical data, pathological changes and immunohistochemical finding were studied in 3 cases of the tumor with review of the literatures. Results All the tumors were located in intraspinal cord, the clinical finding and radiologic imagine were similar to other types of ependymoma. Pathologically, the tumor cells presented as long spindle glial cells forming atypical perivascular rosettes, and reacted with GFAP weekly or negatively, but vimentin and EMA strong positive,which may be differentiated from the astrocytomas and Schwannomas. Its prognosis was similiar to another types of ependymoma. Conclusions The tumor consists of the bipolar long spindle cell forming perivascular rosettes, and the "tanycyte" origines from Greek word"tanyos" (meaning stretching). The term "tanycytic ependymoma" can be best translated into "stretching cell ependymoma".